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基因表达产品
℡ 4000-520-616
℡ 4000-520-616
Zyagen/WIPI2 Antibody/9781/1 Ea
产品编号:9781
市  场 价:¥5900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$295.00
品      牌: Zyagen
公      司:Zyagen
公司分类:
Zyagen/WIPI2 Antibody/9781/1 Ea
商品介绍

Background

WIPI2Antibody:WDrepeatproteinsplayaroleinmanyessentialBIOLOGicfunctions,regulatingtheassemblyofmultiproteincomplexesbypresentingabeta-propellerplatformforsimultaneousandreversIBLeprotein-proteininteractions.WIPI2,alsoknownasATG18BorATG21,isahumanhomologtoyeastATG18andcontainsthreeWDrepeatsandhasa7-bladedpropellerstructurewithaconservedmotifthatfacilitatesitsinteractionwithotherproteins.ItisrecruitedtoearlyautophagosomalstructuresalongwithAtg16LandULK1andisrequiredfortheformationofLC3-positiveautophagosomes.AlongwiththehighlyrelatedWIPI1,WIPI2isfoundattheplasmamembraneinadditiontoautophagosomalmembranes.

 

Description
WIPI2 Antibody
WesternblotanalysisofWIPI2inhumantestistissuelysatewithWIPI2antibodyat1μg/mL

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Specifications

AdditionalNames
WIPI2Antibody:WDrepeatdomainphosphoinositideinteracting2,WIPI-2,WD40repeatproteininteractingwithphosphoinositides2,WIPI49-likeprotein2,ATG18B,ATG21,CGI-50
Reference

  • SmithTF.DiversityofWD-repeatproteins.Subcell.Biochem.2008;48:20-30.
  • PolsonHE,deLartiqueJ,RigdenDJ,etal.MammalianATG18(WIPI2)localizestomoegasome-anchoredphagophoresandpositivelyregulatesLC3lipidation.Autophagy2010;6:506-22.
  • Proikas-CezanneTandRobenekH.Freeze-fracturereplicaimmunolabellingrevealshumanWIPI-1andWIPI-2asmembraneproteinsofautophagosomes.J.Cell.Mol.Med.2011;15:2007-10.]
Formulation
PhysicalState:Liquid 

Concentration:1mg/mL
ProteinGINumber
7661580
ProteinAccessionNumber
NP_056425
MolecularWeight
50kDa
Disclaimer
Thisproductisforresearchuseonly.
TestedApplication
E,WB
Storage
WIPI2antibodycanbestoredat4ËšCforthreemonthsand-20ËšC,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
BlockingPeptide
Cat.No.ZP-7103-WIPI2Peptide
UserNote
Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
Conjugate
None
Purification
WIPI2Antibodyisaffinitychromatographypurifiedviapeptidecolumn.
Clonality/Clone
ThisisapolyclonalWIPI2Antibody.
Host
WIPI2antibodywasraisedinrabbit.

Pleaseuseanti-rabbitsecondaryantibodies.
Specificity
WIPI2antibodyishumanandratreactive.MultipleisoformsofWIPI2areknowntoexist.WIPI2antibodyispredictedtonotcross-reactwithWIPI1.
Immunogen
RabbitpolyclonalWIPI2antibodywasraisedagainsta17aminoacidpeptideneartheaminoterminusofhumanWIPI2.
Application
WIPI2antibodycanbeusedfordetectionofWIPI2byWesternblotat1-2μg/mL.
Buffer
WIPI2AntibodyissuppliedinPBScontaining0.02%sodiumazide.
SpeciesReactivity
H,R

 

品牌介绍
  • Zyagen Laboratories
    ◆发表日期:2012-4-30
      

     

    Zyagen Laboratories

    美国Zyagen Laboratories公司位于加利福尼亚州的生物硅谷圣地亚哥,是一家著名的提供基因表达产品和服务的生物公司。从2000年到现在,在基因表达方面的研究及产品的推广一直处于全球领先地位。Zyagen Laboratories公司由一批训练有素的高水平的学者与研究人员,同时与发展中国家的科学家在生物制药,生物技术等方面有着广泛的合作。

    Zyagen Laboratories公司开发和生产销售细胞定位,基因表达及其蛋白质产物的定量分析的生命科学研究产品。Zyagen Laboratories也提供组织学和药物分析等与政府和学术机构合作的全球定制研究服务。Zyagen公司正在不断改进和扩大产品和服务线,以满足越来越多的科学家在生物医学、生命科学研究的需求。Zyagen公司的目标是致力提供简单化、完整化,高质量,价格实惠的基因表达产品及服务。

    官方网址:http://www.zyagen.com

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