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基因表达产品
℡ 4000-520-616
℡ 4000-520-616
Zyagen/TWEAK Recombinant Protein/7896/1 Ea
产品编号:7896
市  场 价:¥2940.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$147.00
品      牌: Zyagen
公      司:Zyagen
公司分类:
Zyagen/TWEAK Recombinant Protein/7896/1 Ea
商品介绍

Background

TWEAK belongs to the TNF family of ligands and signals through TWEAKR also known as TNFRSF12A. TWEAK is expressed in a variety of tissues, including the adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK has the ability to induce NFkB activation and chemokine secretion, and to exert an apoptotic activity in certain cells, such as HT-29 human adenocarcinoma cells when cultured in the presence of IFN-γ. TWEAK also promotes proliferation and migration of endothelial cells. Recombinant human TWEAK is a soluble 17.0 kDa polypeptide (154 amino acid residues) comprising the TNF homologous region of TWEAK and is generated by proteolytic processing of the full length membrane anchored TWEAK protein.

 

Specifications

Additional Names
TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3-Ligand
Preparation
Assay #1: The ED50 was determined by the dose - dependent stimulation of IL - 8 production by Human PBMC is less than 10 ng/ml. 

Assay #2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN - ?.The ED50 for this effect is between 30 - 45 ng/ml.
Location
MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH
Source
E. coli
Reactivity
n/a
Tested Application
n/a
Storage
The lyophilized TWEAK recombinant protein is stable for at least 2 years from date of receipt at -20ËšC. Reconstituted TWEAK is stable for at least 3 months when stored in working aliquots with a carrier protein at -20ËšC. As with any protein, exposing TWEAK recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Species Reactivity
n/a
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

 

品牌介绍
  • Zyagen Laboratories
    ◆发表日期:2012-4-30
      

     

    Zyagen Laboratories

    美国Zyagen Laboratories公司位于加利福尼亚州的生物硅谷圣地亚哥,是一家著名的提供基因表达产品和服务的生物公司。从2000年到现在,在基因表达方面的研究及产品的推广一直处于全球领先地位。Zyagen Laboratories公司由一批训练有素的高水平的学者与研究人员,同时与发展中国家的科学家在生物制药,生物技术等方面有着广泛的合作。

    Zyagen Laboratories公司开发和生产销售细胞定位,基因表达及其蛋白质产物的定量分析的生命科学研究产品。Zyagen Laboratories也提供组织学和药物分析等与政府和学术机构合作的全球定制研究服务。Zyagen公司正在不断改进和扩大产品和服务线,以满足越来越多的科学家在生物医学、生命科学研究的需求。Zyagen公司的目标是致力提供简单化、完整化,高质量,价格实惠的基因表达产品及服务。

    官方网址:http://www.zyagen.com

    咨询与订购:苏州蚂蚁淘生物科技有限公司 免费电话:4000-520-616

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