Zyagen/PUMA Fragment Recombinant Protein/7603/1 Ea,Zyagen,,Zyagen,Zyagen Laboratories,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Zyagen/PUMA Fragment Recombinant Protein/7603/1 Ea

产品编号：7603

市场价：¥3580.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>其它重组蛋白>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$179.00

品牌： Zyagen

公司：Zyagen

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商品介绍

Background

Peroxisome Proliferator-Activated Receptor Gamma Ligand-Binding Domain (human, recombinant)

Human PPAR gamma (isoform 1) ligand binding domain (amino acids residues 206 -477), expressed in E.coli containing a non-cleavable N-terminal His₆-tag. MW = 32.4 kD.

Peroxisome proliferator-activated receptor gamma also known as NR1C3 (nuclear receptor subfamily 1, group C, member 3) is a nuclear receptor encoded by the PPARG gene. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. PPAR gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.

PPAR gamma influences the storage of fatty acids in adipose tissue and is part of the adipocyte differentiation program that induces the maturation of pre-adipocytes into fat cells. Most of the PPAR gamma target genes in adipose tissue are directly implicated in lipogenic pathways, including regulation of lipoprotein lipase (LPL), adipocyte fatty acid binding protein (A-FABP or AP2), acyl-CoA synthase and fatty acid transport protein (FATP). In addition, PPAR gamma is a direct target gene of the transcription factor sterol response element binding protein 1 (SREBP1) emphasizing the cooperative and additive functions between these two types of receptor.

Description

Coomassie Blue stained - 4-12% NuPAGE Bis-Tris gel of PPAR gamma under reducing and denaturing conditions. Numbers to the left indicate MW¡¯s of marker proteins. Numbers at the top indicate amount of PPAR gamma loaded/lane (μg).

Specifications

Additional Names

NR1C3, PPARG1, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPAR gamma, PPAR-gamma, nuclear receptor subfamily 1 group C member 3, peroxisome proliferative activated receptor gamma, peroxisome proliferator-activated receptor gamma 1

Tested Application

E, WB

Species

Human

Disclaimer

For research use only.

Purity

>99% by SDS-PAGE

Molecular Weight

32.4 kDa

Formulation

20 mM Tris HCl, pH 8.0, 115 mM NaCl, 20% glycerol, 0.2 mM EDTA, 1 mM DTT

Reference

1. Desvergene et al., (1999) Endocr. Rev. 20, 649-688

2. Kersten, (2000) Nature 405, 421-424

3. Rosen et al., (1999) Mol. Cell 4, 611-617

4. Fajas et al., (1999) Mol. Cell. Biol. 19, 5495-550]

Storage

Store at Ëš80C. After initial thawing of product, aliquot the product into individual tubes and refreeze at -80Ëš80C. Avoid repeated freeze/thaw cycles. NOTE: When stored under the noted conditions, this enzyme is stable at the concentration supplied in its current storage buffer. Procedures such as dilution of the enzyme followed by refreezing, could lead to loss of activity.

User Note

This product ships on dry ice.

Species Reactivity

n/a

品牌介绍

Zyagen Laboratories

◆发表日期：2012-4-30

Zyagen Laboratories

美国Zyagen Laboratories公司位于加利福尼亚州的生物硅谷圣地亚哥，是一家著名的提供基因表达产品和服务的生物公司。从2000年到现在，在基因表达方面的研究及产品的推广一直处于全球领先地位。Zyagen Laboratories公司由一批训练有素的高水平的学者与研究人员，同时与发展中国家的科学家在生物制药，生物技术等方面有着广泛的合作。

Zyagen Laboratories公司开发和生产销售细胞定位，基因表达及其蛋白质产物的定量分析的生命科学研究产品。Zyagen Laboratories也提供组织学和药物分析等与政府和学术机构合作的全球定制研究服务。Zyagen公司正在不断改进和扩大产品和服务线，以满足越来越多的科学家在生物医学、生命科学研究的需求。Zyagen公司的目标是致力提供简单化、完整化，高质量，价格实惠的基因表达产品及服务。

官方网址：http://www.zyagen.com

咨询与订购：苏州蚂蚁淘生物科技有限公司 免费电话：4000-520-616

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